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bp0019cpr18 | Gestation Elicited | CPR2013

Maternal and fetal amino acid metabolism in gestating sows

Guoyao Wu , Fuller W. Bazer , Gregory A. Johnson , Robert C. Burghardt , Xilong Li , Zhaolai Dai , Junjun Wang , Zhenlong Wu

Among livestock species, swine exhibit the most severe naturally-occurring intra-uterine growth restriction (IUGR) primarily due to a reduction in net protein synthesis. Thus, new knowledge about fetal metabolism of amino acids (AA), which are building blocks for proteins and regulators of intracellular protein turnover, can provide a solution to this problem. Among all AA, requirements of glutamate and glutamine by fetal pigs are quantitatively the highest, but cannot b...